Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 1.911


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
GABPAchr21_+_27107671-0.519.1e-03Click!
ELK1chrX_-_475098640.349.9e-02Click!
ELK4chr1_-_205601999-0.272.0e-01Click!
GABPB1chr15_-_506472750.087.0e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_35732629 3.454 CREB3
cAMP responsive element binding protein 3
chr11_+_46722316 3.051 NM_024741
ZNF408
zinc finger protein 408
chr9_+_35732498 2.712 CREB3
cAMP responsive element binding protein 3
chr12_-_6798619 2.406 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr19_+_58694444 2.369 ZNF274
zinc finger protein 274
chr11_+_46722564 2.345 NM_001184751
ZNF408
zinc finger protein 408
chr9_+_35732207 2.311 NM_006368
CREB3
cAMP responsive element binding protein 3
chr12_-_6798528 2.276 NM_133476
ZNF384
zinc finger protein 384
chr9_-_123691442 2.111 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr2_+_109745996 2.084 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr21_-_30365111 2.058 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_-_79789290 2.041 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr16_+_31044849 2.027 STX4
syntaxin 4
chr16_+_31044881 1.993 NM_004604
STX4
syntaxin 4
chr1_+_101361688 1.953 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr19_+_58694381 1.813 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr6_-_32811773 1.736 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr13_-_33760215 1.732 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr19_+_38810461 1.728 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr1_-_38273823 1.726 YRDC
yrdC domain containing (E. coli)
chr15_+_75074417 1.668 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr15_-_89089792 1.662 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr1_-_38273846 1.615 YRDC
yrdC domain containing (E. coli)
chr12_+_124196941 1.614 ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr21_+_43933983 1.612 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_-_38273683 1.576 YRDC
yrdC domain containing (E. coli)
chr5_-_138862342 1.541 NM_198282
TMEM173
transmembrane protein 173
chr5_-_137878808 1.521 ETF1
eukaryotic translation termination factor 1
chr17_-_56595192 1.519 NM_004687
MTMR4
myotubularin related protein 4
chr11_-_6502524 1.501 ARFIP2
ADP-ribosylation factor interacting protein 2
chr15_+_75074714 1.468 CSK
c-src tyrosine kinase
chr1_-_222763081 1.464 NM_001201536
NM_005681
NM_139352
TAF1A


TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa


chr1_-_173446273 1.461 LOC100506023
uncharacterized LOC100506023
chr4_-_2758018 1.460 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr5_-_138862224 1.454 TMEM173
transmembrane protein 173
chr2_-_136743076 1.453 DARS
aspartyl-tRNA synthetase
chr1_+_36396673 1.431 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr1_-_38273852 1.429 NM_024640
YRDC
yrdC domain containing (E. coli)
chr6_-_137113166 1.429


chr6_-_33290678 1.422 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr2_-_136743189 1.417 NM_001349
DARS
aspartyl-tRNA synthetase
chr2_-_7005764 1.416 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_+_73356179 1.404 NM_006346
PIBF1
progesterone immunomodulatory binding factor 1
chr6_+_18155535 1.399 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr1_+_213224530 1.395 NM_001136138
NM_012424
RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1

chr7_-_45151272 1.388 TBRG4
transforming growth factor beta regulator 4
chr6_-_32812189 1.387 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr4_-_100867868 1.380 NM_001031723
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr1_+_169337193 1.372 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr16_-_81110803 1.367 NM_001100873
NM_152337
C16orf46

chromosome 16 open reading frame 46

chrX_-_40594774 1.360 NM_004229
MED14
mediator complex subunit 14
chr6_-_29527477 1.346 UBD
ubiquitin D
chr18_-_72264808 1.342 LOC400657
uncharacterized LOC400657
chr18_-_72265038 1.337 LOC400657
uncharacterized LOC400657
chr8_+_145582267 1.335 NM_024531
GPR172A
G protein-coupled receptor 172A
chr1_+_55181494 1.323 NM_004623
TTC4
tetratricopeptide repeat domain 4
chr4_+_110736636 1.318 NM_018983
NM_032993
GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr7_-_97601654 1.306


chr12_-_498256 1.292 KDM5A
lysine (K)-specific demethylase 5A
chr11_-_6502563 1.281 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr18_+_51795848 1.280 NM_007195
POLI
polymerase (DNA directed) iota
chrX_-_40594663 1.278 MED14
mediator complex subunit 14
chr9_+_130548326 1.269 CDK9
cyclin-dependent kinase 9
chr3_-_79068542 1.265 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr19_+_7069686 1.263 ZNF557
zinc finger protein 557
chr2_-_231084600 1.260 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr4_-_2757750 1.256 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr17_+_77020278 1.254 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_-_82461857 1.249 FAM46A
family with sequence similarity 46, member A
chr3_-_48481518 1.245 NM_024661
CCDC51
coiled-coil domain containing 51
chr7_-_128695181 1.240 NM_001191028
NM_012470
TNPO3

transportin 3

chr9_+_72873985 1.236 SMC5
structural maintenance of chromosomes 5
chr11_-_60719116 1.233 NM_016582
SLC15A3
solute carrier family 15, member 3
chr16_+_31044414 1.226 STX4
syntaxin 4
chr2_+_110371887 1.225 NM_023016
ANKRD57
ankyrin repeat domain 57
chr17_+_4981754 1.218 ZFP3
zinc finger protein 3 homolog (mouse)
chr16_+_31085751 1.206 ZNF646
zinc finger protein 646
chr4_+_164415841 1.206 C4orf43
chromosome 4 open reading frame 43
chr2_-_136743037 1.205 DARS
aspartyl-tRNA synthetase
chr20_-_48532067 1.188 NM_006038
SPATA2
spermatogenesis associated 2
chr15_+_59063389 1.180 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr17_+_79633724 1.163 NM_199287
CCDC137
coiled-coil domain containing 137
chr1_+_24069961 1.152 TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr3_-_150264280 1.148 NM_014445
SERP1
stress-associated endoplasmic reticulum protein 1
chr4_-_100867726 1.148 DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr3_-_72897575 1.143 SHQ1
SHQ1 homolog (S. cerevisiae)
chr3_-_150264264 1.133 SERP1
stress-associated endoplasmic reticulum protein 1
chr5_-_87564615 1.126 NM_153354
TMEM161B
transmembrane protein 161B
chr1_+_93811463 1.125 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr17_+_4981721 1.122 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr17_+_34891340 1.111 NM_178517
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr6_+_160148608 1.110 NM_152857
WTAP
Wilms tumor 1 associated protein
chr19_+_7069454 1.102 NM_001044387
NM_001044388
NM_024341
ZNF557


zinc finger protein 557


chr22_+_39898248 1.102 NM_019008
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like
chr1_+_183155393 1.101 LAMC2
laminin, gamma 2
chr8_+_22462273 1.097 KIAA1967
KIAA1967
chr8_+_22462286 1.086 KIAA1967
KIAA1967
chr18_+_72166568 1.082 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr13_-_95248401 1.076 TGDS
TDP-glucose 4,6-dehydratase
chr7_-_2281822 1.076 NM_013393
FTSJ2
FtsJ homolog 2 (E. coli)
chr17_-_79876027 1.076 SIRT7
sirtuin 7
chr7_-_128694823 1.076 TNPO3
transportin 3
chr2_-_27603249 1.073 NM_001201459
ZNF513
zinc finger protein 513
chr1_+_24069855 1.073 NM_003198
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr13_-_73356058 1.072 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr19_-_16683188 1.071 NM_024881
SLC35E1
solute carrier family 35, member E1
chr10_+_114154522 1.070 ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_-_51057894 1.069 NM_032802
SPPL2A
signal peptide peptidase-like 2A
chr10_-_121302149 1.048 NM_001005339
RGS10
regulator of G-protein signaling 10
chr20_+_388941 1.046 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr13_-_73355969 1.045 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr1_+_118472364 1.041 NM_006784
WDR3
WD repeat domain 3
chr1_-_52499432 1.038 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chrX_-_40594949 1.038 MED14
mediator complex subunit 14
chr4_+_146540522 1.035 NM_172250
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr17_-_33905556 1.033 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr11_+_61159818 1.033 NM_001173990
NM_001173991
NM_016499
TMEM216


transmembrane protein 216


chr5_-_60458228 1.032 NM_001048249
C5orf43
chromosome 5 open reading frame 43
chr6_-_32806545 1.030 NM_000544
NM_018833
TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

chr14_-_45431121 1.029 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr11_+_63974144 1.020 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr7_-_2281797 1.014 FTSJ2
FtsJ homolog 2 (E. coli)
chr3_-_69101236 1.013 NM_007114
TMF1
TATA element modulatory factor 1
chr8_-_134309448 1.011 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr9_+_127631500 1.009 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr6_-_82462374 1.008 NM_017633
FAM46A
family with sequence similarity 46, member A
chr10_+_97889655 1.003 ZNF518A
zinc finger protein 518A
chr1_+_101361649 1.002 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr9_+_130548358 0.995 CDK9
cyclin-dependent kinase 9
chr14_+_74353507 0.990 ZNF410
zinc finger protein 410
chr7_-_128695118 0.990 TNPO3
transportin 3
chr16_+_75600248 0.987 NM_007285
GABARAPL2
GABA(A) receptor-associated protein-like 2
chr5_+_140071014 0.986 NM_012208
HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr2_+_234160216 0.986 NM_001190266
NM_001190267
NM_017974
NM_030803
NM_198890
ATG16L1




ATG16 autophagy related 16-like 1 (S. cerevisiae)




chr8_+_145703439 0.984 PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr3_-_187871816 0.982 LPP-AS2
LPP antisense RNA 2 (non-protein coding)
chr20_+_60877939 0.982 ADRM1
adhesion regulating molecule 1
chr22_+_38453478 0.981 PICK1
protein interacting with PRKCA 1
chr5_+_34656482 0.977 RAI14
retinoic acid induced 14
chr5_+_158690265 0.976 UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr2_+_219081864 0.975 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_27603584 0.975 NM_144631
ZNF513
zinc finger protein 513
chr17_+_77020229 0.975 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr11_+_63974190 0.975 FERMT3
fermitin family member 3
chr2_-_233415206 0.972 NM_145702
TIGD1
tigger transposable element derived 1
chr11_+_61160098 0.970 TMEM216
transmembrane protein 216
chr19_+_7459964 0.969 NM_015318
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr11_+_118307072 0.969 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr14_+_76618272 0.968 C14orf118
chromosome 14 open reading frame 118
chr5_-_137878915 0.963 NM_004730
ETF1
eukaryotic translation termination factor 1
chr20_+_60878048 0.963 ADRM1
adhesion regulating molecule 1
chr16_+_75600276 0.962 GABARAPL2
GABA(A) receptor-associated protein-like 2
chr8_+_82192717 0.961 NM_001444
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr16_+_31085722 0.960 NM_014699
ZNF646
zinc finger protein 646
chr10_-_22292362 0.958 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr20_+_60878024 0.958 NM_007002
NM_175573
ADRM1

adhesion regulating molecule 1

chr17_-_79876035 0.953 NM_016538
SIRT7
sirtuin 7
chr11_+_61129831 0.949 TMEM138
transmembrane protein 138
chr1_-_43855473 0.948 NM_052877
NM_201542
MED8

mediator complex subunit 8

chr13_+_50070096 0.948 PHF11
PHD finger protein 11
chr22_+_38004676 0.946 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr5_-_137878901 0.943 ETF1
eukaryotic translation termination factor 1
chr6_+_170863420 0.941 NM_001172085
NM_003194
TBP

TATA box binding protein

chr5_-_60458146 0.940 C5orf43
chromosome 5 open reading frame 43
chr5_-_102455781 0.940 NM_017676
GIN1
gypsy retrotransposon integrase 1
chr20_+_44486219 0.934 NM_080752
ZSWIM3
zinc finger, SWIM-type containing 3
chr4_-_153456152 0.933 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr16_+_56485423 0.931 NM_018233
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr17_-_1012257 0.930 NM_001092
ABR
active BCR-related gene
chr5_+_176730779 0.928 PRELID1
PRELI domain containing 1
chr20_+_61904183 0.926 ARFGAP1
ADP-ribosylation factor GTPase activating protein 1
chr1_-_228594466 0.925 NM_145214
TRIM11
tripartite motif containing 11
chr2_-_233415266 0.924 TIGD1
tigger transposable element derived 1
chr17_-_79875995 0.922 SIRT7
sirtuin 7
chr10_-_79789164 0.922 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr7_-_77045706 0.920 NM_017439
PION
pigeon homolog (Drosophila)
chr5_+_34656595 0.919 NM_001145520
RAI14
retinoic acid induced 14
chr14_-_24657986 0.915 IPO4
importin 4
chr5_-_114961702 0.914 NM_001164468
NM_001164469
NM_181836
TMED7-TICAM2

TMED7
TMED7-TICAM2 readthrough

transmembrane emp24 protein transport domain containing 7
chr3_+_122399665 0.914 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr8_+_124780742 0.914 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr14_-_24658010 0.913 NM_024658
IPO4
importin 4
chr12_+_21654698 0.912 NM_016072
GOLT1B
golgi transport 1B
chr17_-_74497406 0.912 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr10_+_12391471 0.911 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr20_+_61904158 0.905 NM_018209
NM_175609
ARFGAP1

ADP-ribosylation factor GTPase activating protein 1

chr11_-_22647329 0.903 NM_022725
FANCF
Fanconi anemia, complementation group F
chr5_+_34656367 0.902 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr12_-_110888152 0.901 NM_005719
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr22_+_51021454 0.900 LOC100144603
uncharacterized transcript
chr3_-_72897576 0.899 NM_018130
SHQ1
SHQ1 homolog (S. cerevisiae)
chr13_+_38923964 0.891 UFM1
ubiquitin-fold modifier 1
chr6_+_33422319 0.890 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr1_-_156698188 0.890 ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr6_+_31553955 0.889 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr5_+_80597401 0.887 NM_001131035
NM_001131036
NM_032280
ZCCHC9


zinc finger, CCHC domain containing 9


chr3_+_130612806 0.886 NM_001199179
NM_001001485
NM_001199183
NM_001199184
NM_001199185
NM_014382
NM_001001486
NM_001001487
ATP2C1







ATPase, Ca++ transporting, type 2C, member 1







chr12_-_110318178 0.885 NM_016433
GLTP
glycolipid transfer protein
chr2_+_99771535 0.884 NM_001204830
LIPT1
lipoyltransferase 1
chr3_+_9404706 0.877 NM_001114092
NM_015453
THUMPD3

THUMP domain containing 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 9.66e-33 GO:0044260 cellular macromolecule metabolic process
1.28 6.14e-24 GO:0043170 macromolecule metabolic process
1.41 7.33e-24 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.91 6.42e-23 GO:0006396 RNA processing
1.51 7.04e-23 GO:0010467 gene expression
1.52 2.30e-22 GO:0016070 RNA metabolic process
1.44 1.28e-21 GO:0090304 nucleic acid metabolic process
1.21 3.62e-19 GO:0044237 cellular metabolic process
1.31 1.80e-15 GO:0034641 cellular nitrogen compound metabolic process
1.67 3.82e-15 GO:0046907 intracellular transport
1.82 4.26e-15 GO:0016071 mRNA metabolic process
1.29 6.87e-14 GO:0006807 nitrogen compound metabolic process
1.31 6.63e-13 GO:0071841 cellular component organization or biogenesis at cellular level
1.90 9.65e-13 GO:0006397 mRNA processing
1.26 2.72e-12 GO:0071840 cellular component organization or biogenesis
1.17 3.24e-12 GO:0044238 primary metabolic process
1.32 5.42e-12 GO:0044267 cellular protein metabolic process
1.57 7.62e-12 GO:0045184 establishment of protein localization
1.57 9.26e-12 GO:0015031 protein transport
1.96 3.91e-11 GO:0008380 RNA splicing
2.19 8.18e-11 GO:0022613 ribonucleoprotein complex biogenesis
1.15 8.22e-11 GO:0008152 metabolic process
1.44 9.73e-11 GO:0051641 cellular localization
1.48 1.18e-10 GO:0008104 protein localization
1.09 2.25e-10 GO:0009987 cellular process
2.12 3.34e-10 GO:0071843 cellular component biogenesis at cellular level
1.45 1.19e-09 GO:0051649 establishment of localization in cell
1.41 1.90e-09 GO:0033036 macromolecule localization
2.34 2.55e-09 GO:0048193 Golgi vesicle transport
1.92 6.67e-09 GO:0034660 ncRNA metabolic process
2.07 6.92e-09 GO:0000375 RNA splicing, via transesterification reactions
1.23 2.21e-08 GO:0060255 regulation of macromolecule metabolic process
1.26 2.42e-08 GO:0071842 cellular component organization at cellular level
1.35 2.74e-08 GO:0006996 organelle organization
2.05 3.24e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.05 3.24e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
1.22 7.67e-08 GO:0016043 cellular component organization
1.33 9.52e-08 GO:0034645 cellular macromolecule biosynthetic process
1.33 1.09e-07 GO:0009059 macromolecule biosynthetic process
1.61 1.94e-07 GO:0070727 cellular macromolecule localization
1.61 2.21e-07 GO:0034613 cellular protein localization
2.24 6.13e-07 GO:0042254 ribosome biogenesis
1.49 7.43e-07 GO:0016192 vesicle-mediated transport
1.54 9.07e-07 GO:0009057 macromolecule catabolic process
1.58 1.38e-06 GO:0044265 cellular macromolecule catabolic process
1.67 1.69e-06 GO:0006886 intracellular protein transport
1.96 2.33e-06 GO:0034470 ncRNA processing
1.76 2.87e-06 GO:0006366 transcription from RNA polymerase II promoter
1.68 3.82e-06 GO:0030163 protein catabolic process
1.71 4.53e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
1.19 1.21e-05 GO:0031323 regulation of cellular metabolic process
1.27 1.42e-05 GO:0043412 macromolecule modification
1.68 1.59e-05 GO:0044257 cellular protein catabolic process
1.17 1.88e-05 GO:0019222 regulation of metabolic process
1.20 2.51e-05 GO:0019538 protein metabolic process
1.18 2.84e-05 GO:0080090 regulation of primary metabolic process
1.27 2.97e-05 GO:0006464 protein modification process
1.22 3.00e-05 GO:0010468 regulation of gene expression
1.66 5.52e-05 GO:0043632 modification-dependent macromolecule catabolic process
1.34 5.92e-05 GO:0044085 cellular component biogenesis
1.66 7.65e-05 GO:0019941 modification-dependent protein catabolic process
1.34 8.66e-05 GO:0044248 cellular catabolic process
1.66 9.88e-05 GO:0006511 ubiquitin-dependent protein catabolic process
2.38 1.38e-04 GO:0006353 transcription termination, DNA-dependent
1.39 1.83e-04 GO:0033554 cellular response to stress
1.35 2.33e-04 GO:0007049 cell cycle
1.67 4.55e-04 GO:0010608 posttranscriptional regulation of gene expression
1.54 6.44e-04 GO:0016032 viral reproduction
1.47 9.26e-04 GO:0006974 response to DNA damage stimulus
1.27 1.05e-03 GO:0009056 catabolic process
2.28 1.20e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.20 1.23e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.19 1.24e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.85 1.26e-03 GO:0010498 proteasomal protein catabolic process
1.85 1.26e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.20 1.53e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.20 1.75e-03 GO:0044249 cellular biosynthetic process
1.35 2.00e-03 GO:0006351 transcription, DNA-dependent
1.48 3.34e-03 GO:0016044 cellular membrane organization
2.11 3.37e-03 GO:0006364 rRNA processing
2.19 4.03e-03 GO:0006354 transcription elongation, DNA-dependent
1.48 4.44e-03 GO:0061024 membrane organization
1.40 4.95e-03 GO:0051726 regulation of cell cycle
1.18 5.19e-03 GO:0031326 regulation of cellular biosynthetic process
1.18 5.33e-03 GO:0009889 regulation of biosynthetic process
2.05 6.28e-03 GO:0016072 rRNA metabolic process
1.52 8.12e-03 GO:0044419 interspecies interaction between organisms
1.18 1.08e-02 GO:0009058 biosynthetic process
2.09 1.15e-02 GO:0051351 positive regulation of ligase activity
1.19 1.19e-02 GO:0051252 regulation of RNA metabolic process
2.20 1.46e-02 GO:0072594 establishment of protein localization to organelle
2.85 1.64e-02 GO:0006903 vesicle targeting
1.51 2.26e-02 GO:0070647 protein modification by small protein conjugation or removal
1.59 2.34e-02 GO:0016567 protein ubiquitination
1.88 2.41e-02 GO:0006399 tRNA metabolic process
2.05 2.44e-02 GO:0022618 ribonucleoprotein complex assembly
2.07 2.61e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.09 2.78e-02 GO:0031123 RNA 3'-end processing
2.56 2.83e-02 GO:0006888 ER to Golgi vesicle-mediated transport
1.17 2.93e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 3.02e-02 GO:0048011 nerve growth factor receptor signaling pathway
3.17 3.47e-02 GO:0007030 Golgi organization
1.61 3.64e-02 GO:0071156 regulation of cell cycle arrest
1.63 3.68e-02 GO:0033365 protein localization to organelle
1.81 3.77e-02 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
1.55 3.86e-02 GO:0032446 protein modification by small protein conjugation
1.30 4.15e-02 GO:0008219 cell death
1.46 4.27e-02 GO:0007264 small GTPase mediated signal transduction
1.99 4.31e-02 GO:0071826 ribonucleoprotein complex subunit organization
2.13 4.70e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.69 4.87e-02 GO:0043687 post-translational protein modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 3.81e-58 GO:0005622 intracellular
1.18 2.43e-56 GO:0044424 intracellular part
1.23 2.17e-48 GO:0043227 membrane-bounded organelle
1.23 2.32e-48 GO:0043231 intracellular membrane-bounded organelle
1.20 5.75e-46 GO:0043229 intracellular organelle
1.20 1.18e-45 GO:0043226 organelle
1.31 2.95e-38 GO:0005634 nucleus
1.51 1.22e-29 GO:0044428 nuclear part
1.53 5.16e-27 GO:0031981 nuclear lumen
1.46 1.18e-25 GO:0070013 intracellular organelle lumen
1.44 7.51e-25 GO:0031974 membrane-enclosed lumen
1.45 1.60e-24 GO:0043233 organelle lumen
1.25 2.87e-24 GO:0044446 intracellular organelle part
1.24 2.22e-23 GO:0044422 organelle part
1.16 5.36e-19 GO:0005737 cytoplasm
1.49 1.14e-15 GO:0005654 nucleoplasm
1.79 1.14e-14 GO:0030529 ribonucleoprotein complex
1.79 2.36e-14 GO:0005730 nucleolus
1.25 2.71e-13 GO:0032991 macromolecular complex
1.17 2.65e-12 GO:0044444 cytoplasmic part
1.58 4.04e-11 GO:0044451 nucleoplasm part
2.38 6.96e-11 GO:0005681 spliceosomal complex
1.31 3.08e-10 GO:0005829 cytosol
1.98 3.18e-09 GO:0016604 nuclear body
1.25 7.96e-09 GO:0043228 non-membrane-bounded organelle
1.25 7.96e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.04 4.60e-08 GO:0005623 cell
1.04 6.27e-08 GO:0044464 cell part
2.92 5.01e-06 GO:0015030 Cajal body
1.19 1.67e-05 GO:0043234 protein complex
3.23 3.70e-04 GO:0044452 nucleolar part
3.31 5.00e-04 GO:0005689 U12-type spliceosomal complex
2.23 1.54e-03 GO:0030117 membrane coat
2.23 1.54e-03 GO:0048475 coated membrane
2.11 1.91e-03 GO:0071013 catalytic step 2 spliceosome
1.29 2.79e-03 GO:0005794 Golgi apparatus
1.19 3.98e-03 GO:0031090 organelle membrane
2.12 4.10e-02 GO:0016605 PML body
3.40 4.67e-02 GO:0030663 COPI coated vesicle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 3.78e-20 GO:0005515 protein binding
1.10 5.47e-18 GO:0005488 binding
1.29 1.28e-15 GO:0003676 nucleic acid binding
1.59 1.49e-13 GO:0003723 RNA binding
1.24 2.07e-05 GO:0008270 zinc ion binding
1.21 1.62e-04 GO:0000166 nucleotide binding
1.82 3.79e-04 GO:0008168 methyltransferase activity
1.76 1.27e-03 GO:0016741 transferase activity, transferring one-carbon groups
1.19 2.56e-03 GO:0003677 DNA binding
1.20 8.46e-03 GO:0035639 purine ribonucleoside triphosphate binding
2.00 1.76e-02 GO:0008135 translation factor activity, nucleic acid binding
2.82 1.78e-02 GO:0008173 RNA methyltransferase activity
1.19 1.81e-02 GO:0017076 purine nucleotide binding
1.17 1.82e-02 GO:0046914 transition metal ion binding
1.19 2.18e-02 GO:0032553 ribonucleotide binding
1.19 2.18e-02 GO:0032555 purine ribonucleotide binding
1.38 3.98e-02 GO:0016874 ligase activity